Hock+Hoof is located in the historical Hotel Alexandria building in downtown Los Angeles, though the restaurant is not related to or inside the hotel's facilities. The building was originally opened on on February 12, 1906 as an 8-story luxury hotel at the southwest corner of Spring and 5th Streets in downtown Los Angeles. It was designed by architect John B. Parkinson and constructed by developers Albert C. Bilicke and Robert A. Rowan. The Hotel Alexandria was the most luxurious hotel in Los Angeles for a number of years until the construction of the Biltmore Hotel in 1923. The building has served as a location for countless films, including Se7en (1995), A Midnight Romance (1919), Dreamgirls (2006), Water for Elephants (2011), Spider-Man 3 (2007), and Domino (2005).